OPEN CALL FOR MSCA - POSTDOCTORAL FELLOWSHIP

The selected candidate will join the Badalona Neuromuscular Research Group (GRENBA), an interdisciplinary team based at the IGTP.
The group integrates clinical, experimental, and computational approaches to investigate rare neuromuscular diseases, with a particular focus on myotonic dystrophy type 1 (DM1).
The fellow will contribute to the research line focused on the application of long-read sequencing technologies to study the repetitive region associated with DM1.
Additionally, the candidate will develop and implement innovative transcriptomic and metabolomic methodologies aimed at uncovering novel disease mechanisms.
MAIN RESPONSIBILITIES The research project will focus on the comprehensive characterization of the pathogenic DMPK repeat expansion associated with myotonic dystrophy type 1 (DM1), using cutting-edge long-read sequencing technologies.
The specific tasks and responsibilities include.
Design and execution of experiments involving long-read sequencing to analyse repeat length, sequence interruptions, somatic mosaicism, and methylation patterns at the DMPK locus.
Bioinformatic processing and analysis of long-read data, including the development or adaptation of pipelines to study repetitive and epigenetically regulated regions.
Integration of multi-omics data, including transcriptomic and metabolomic datasets, to investigate disease mechanisms and identify potential biomarkers.
Collaboration with clinical and experimental teams to ensure translational relevance of the findings and contributions.
Preparation of scientific publications, conference presentations, and reports derived from the project outcomes.
Engagement with the broader MSCA network, including participation in training activities and workshops.
QUALIFICATIONS AND EXPERIENCIE Q UALIFICATIONS AND EXPERIENCE.
Candidate must comply with the  MSCA Postdoctoral Fellowships (HORIZON-MSCA--PF-01)  eligibility criteria set by the call.
Supported fellows.
Must be in possession of doctoral degree.
At the call deadline (), supported researchers must have a maximum of 8 years full time equivalent experience in research, measured from the date that the researcher was in a possession of a doctoral degree and certified by appropriate documents.
Nationality.
Any.
Mobility.
The researcher must not have resided or carried out his/her main activity (work, studies, etc.) in the country of the host organization for more than 12 months in the 3 years immediately prior to the deadline.
Researchers wishing to reintegrate from a third country must either be based in a third country at the call deadline, or have moved directly from a third country to an EU Member State or Horizon Europe Associated Country within the last 12 months before the call deadline.
Must be fluent in English (both written and spoken) Candidates with an oustanding record of Research achievements and publications We are looking for talented and innovative scientist with a strong background in molecular genetics, genomics, bioinformatics, and/or neurobiology.
We seek highly motivated researchers capable of working both independently and as part of a multidisciplinary team.
Ideal candidates will have demonstrated experience in two or more of the following areas Long-read sequencing technologies.
Analysis of repetitive DNA regions, structural variants, or somatic mosaicism.
Transcriptomic or epigenomic profiling.
Multi-omics data integration (transcriptomics, metabolomics, epigenomics).
Bioinformatics and data analysis in a Linux/Unix environment.
Rare disease research, especially in neuromuscular or neurogenetic disorders.
WHAT WE OFFER Contribution for the recruited researcher per person monthly.
Living allowance.
€ Mobility allowance.
710€ Family allowance (if applicable).
660€ x % covered by the beneficiary Long-term leave allowance (if applicable).
€ The candidate can be only incorporated with an obtention of a MSCA-PF- or similar.
Flexible payment (childminding vouchers).
23 days holiday and 5 days for personal matters +2 days for Easter + 2 days for Christmas.
Training capsules by the company.
Be part of an excellent multidisciplinary research centre with the HRS4R badge.
Location on the Can Ruti Campus, a first-class translational research environment in the Barcelona area, in a very stimulating scientific environment.
The IGTP offers a supportive, friendly and collaborative ecosystem to promote professional development and help you achieve your research goals.