DIRECTOR BIOINFORMATICS

Job Title.
Director Bioinformatics   Grade F     Location.
Barcelona, Spain     Salary.
Competitive & Excellent Benefits Package        Introduction to Role.
Are you ready to explore and innovate in a dynamic environment? AstraZeneca is seeking a highly skilled Bioinformatics leader with a strong desire to enable multi-omics biology, at the bulk and spatial level, in drug discovery and development.
This position offers a rare opportunity to gain experience in a variety of computational approaches, work with industry leaders, and contribute directly to the development of future drugs across many diseases.
Responsibilities.
Manage a team of expert bioinformaticians and oversee the design and execution of multiple novel informatics solutions     Leads data science projects of defined scope, potentially across multiple locations     Define and oversee training and advice to collaborators on optimal use of key data, platforms and the appropriate use of complex informatics solutions     Collaborates across the Astrazeneca Informatic communities to develop best practices and cross functional opportunities that drive value     Oversight of partnerships with multiple third-parties, academic or outsourced partners to shape and drive project outcomes and knowledge building     Build in-silico capabilities to advance multi-omics technologies that measure transcripts, proteins, and metaboloites at both the bulk and spatial levels to discover novel mechanisms of action for our compounds     Drive hypothesis generation by applying computational biology approaches, data integration, and combining biological knowledge     Implement new predictive capabilities using computational biology to translate omics data into biological insights      Collaborate with academic research groups and contribute to publications in peer-reviewed journals     Help educate and train AstraZeneca colleagues in omics data intepretation and related areas           Requirements.
PhD in computational biosciences (e.
., computational biology, bioinformatics, genomics or computer science) is preferred; or MSc (or equivalent) with experience in independent research in high-throughput omics data will also be considered     Experience designing bioinformatic solutions for computational toxicology, predictive safety and off-target liabilities.
Demonstrated experience in transcriptomics, proteomics or metabolomics data analysis.
Skill-sets in additional computational biology domains are a plus.
Demonstrated expertise in R or Python, together with data visualisation frameworks (e.
., ggplot2, matplotlib or others)     Use of basic statistics (e.
., parametric and non-parametric tests, p-values, correlation metrics, PCA) and good experimental design practices (e.
., batch effects, confounding factors)     Demonstrated experiences or a keen interest in learning data science techniques, such as machine learning, for biological problems     Team player mindset and ability to explain complex topics to scientists from other disciplines         Desirable.
Proven track record of publishing relevant results and tools in peer-reviewed journals, conferences, and other scientific proceedings.
Experience in independent scientific research     Knowledge of molecular mechanisms of disease or human biomedicine, particularly in a drug safety context     Excellent written and verbal communication, business analysis, and consultancy skills      Experience in a complex global organization     Excellent ability to work on multiple projects at the same time     Knowledge of drug discovery or pharmaceutical development       When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines.
In-person working gives us the platform we need to connect, work at pace and challenge perceptions.
That's why we work, on average, a minimum of three days per week from the office.
But that doesn't mean we're not flexible.
We balance the expectation of being in the office while respecting individual flexibility.
Join us in our unique and ambitious world.
At AstraZeneca, we are a dedicated distributed team that's powering the company to better serve patients every day, and we follow the science to explore and innovate.
We are working towards treating, preventing, modifying and even curing some of the world's most complex diseases.
We have built our business around our passion for science.
Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs.
We are always listening and learning from people who live with the diseases our medicines treat.
It enables us to better understand their needs and, ultimately, diagnose and design the right treatments to impact patients' lives.
Are you ready to make an impact on patients' lives? Join us at AstraZeneca where we are driven by our shared belief in what science can do.
Apply today!   AstraZeneca embraces diversity and equality of opportunity.
We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.
We believe that the more inclusive we are, the better our work will be.
We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.
We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.